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Rams vs 49ers Picks and Predictions NFL Week 10 Monday Night Football

Los Angeles Rams vs San Francisco 49ers picks, predictions, and game preview for this Week 10 Monday Night Football Game.

Rams vs 49ers odds

This Monday Night Football game between the Los Angeles Rams vs San Francisco 49ers is set to kickoff November 15, 2021 at 8:15pm at the Levi’s Stadium in San Francisco.

The latest NFL odds have the Rams listed as a -3.5 point favorite against the spread with the over/under at 50 total points.

The NFL betting public is loving the Rams in this one and currently have 77% of their money behind them as the road favorite.

Los Angeles Rams Betting Preview

The Los Angeles Rams come into this game at 7-2 overall. With Kyler Murray out for the Cardinals and them losing this week to the Carolina Panthers, this is the perfect opportunity for LA to take possession of that top spot in the NFC West. The Rams are coming off that Week 9 loss to the Tennessee Titans 28-16.

Quarterback Matthew Stafford didn’t play well at all and threw two costly interceptions, but there should be no worries because he’ll have a big performance in this one. Our player prop bet will actually be on him, so if you want free access to this NFL Prop then just text “MNF” to me directly at 702-234-0597.

Stafford lost one of his favorite targets this week in practice unfortunately. Wide receiver Robert Woods tore his ACL and will be out for the season.

All eyes will now be on Cooper Kupp, Van Jefferson, and newly acquired Odell Beckham Jr, who will make his Monday Night Football debut for the Rams.

Los Angeles on the road this season have the second best offense in the league that’s putting up an average of 32.2 points per game.

On the road they also have the eighth best defense in the league currently that’s holding opponents to an average of just 18.5 points per game.

LA is 2-4 against the spread in their last 6 games and 1-4 straight up in their last 5 games against San Francisco.

San Francisco 49ers Betting Preview

On the other side of the field, the San Francisco 49ers come into this game at the bottom of the NFC West at 3-5 overall. Last week they lost 31-17 to the Cardinals without Kyler Murray or Deandre Hopkins.

Their backfield played horrendous in that game and now the running backs will have to face the #1 road defense against the run in the league who are only giving up an average of 76.2 rush yards per game.

Quarterback Jimmy Garoppolo and Tight End George Kittle will continue leading this offense, but in order for them to beat this tough Los Angeles team, then running back Elijah Mitchell will need to have a monster game. He’s been a bit banged up and was limited in practice this week, so that might be a lot to ask from Mitchell.

At home this season, the 49ers have one of the worst defenses in the league that give up an average of 29.8 points per game. Their offense at home scores an average of 21 points per game, so now you can see why this team only has 3 wins this season.

The 49ers are 1-5 against the spread in their last 6 games and and the total has gone over in 6 of San Francisco’s last 9 games.

Free NFL Picks:

Our numbers show that the best way to make money on this Los Angeles Rams vs San Francisco 49ers Monday Night Football Game is to take the Rams Team Total to go over the 27.5 total points and lay the -105 price.

Then Click Here for Free NFL Consensus Pick Access on the side in this game. These Consensus Picks have been red hot and are in high demand because they are only released when all five of our expert cappers agree on one pick.

These five experts bring to the table over 130 years of combined knowledge in the sports information industry and all of them really love the side in this matchup, so take advantage of this free consensus pick here.


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