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Diamondbacks vs Giants MLB Picks and Predictions for Tuesday, Sept 28

Arizona Diamondbacks vs San Francisco Giants picks, predictions, and game preview for this Tuesday baseball game.

Diamondbacks vs Giants odds

The Arizona Diamondbacks vs San Francisco is set to go this Tuesday, September 28, 2021 at 9:45pm et at Oracle Park in San Fran. The MLB Odds have the Giants as a -275 money line favorite, -125 on the run line and the over/under is at 8 total runs.

74% of the MLB Betting Public have their money behind San Francisco as the big home favorite.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks come into this game still holding onto the worst record in the league at 50-106 overall with three of their last six games against one of the top teams in baseball right now.

They’ll have Luke Weaver take the mound, who’s a horrible 0-4 on the road this season with a 7.94 ERA and a 1.588 WHIP. With him on the mound in September, they’ve lost 6-1 to the Braves, 8-4 to the Dodgers, and 8-5 to the Rangers.

Weaver is 3-3 with an ERA of 3.16 and 37 strikeouts in 6 appearances vs San Francisco in his career.

Arizona is 2-17 straight up in their last 19 games against San Francisco and the total has gone over in 6 of the Diamondbacks last 9 games.

San Francisco Giants Betting Preview

The San Francisco Giants come into this game still with the best record in the league at 102-54 and will have the rest of their six regular season games played at home.

The good news is that they’ll have their ace Logan Webb get the start. Webb at home this season is an impressive 5-0 with 1.79 ERA and a .961 WHIP. Webb is 2-0 with an ERA of 2.25 and 15 strikeouts in 2 appearances against the Diamondbacks in his career.

San Francisco is 5-1 straight up in their last 6 games against an opponent in the NL and the total has gone over in 5 of San Francisco’s last 5 games when playing at home against Arizona.

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